At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie

About the Role:

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• We are looking for an enthusiastic and organized person with a passion for science and the ability to quickly learn new lab techniques

• Assist with cell culture, transient transfection, expression optimization, DNA preparation, and protein quantification

• Culture mammalian cell lines for DNA transfection with rigorous sterile technique

• Explore potential improvements to the existing protein expression platform under the direction of a senior scientist

• Optimize experimental procedures drawing on available literature and previous results

• Partner in the development of a stable cell line expression platform for research purposes

• Work with bioreactors for transient and stable CHO expression

• Prepare detailed data reports and presents results to peers and colleagues

• Other duties as assigned

• BS/BA degree and 2+ years of relevant experience, including familiarity utilizing any or all of the following: parallel synthesis, lab automation, and purification in the optimization of lead compounds is preferred OR

• MS/MA degree in Synthetic Organic Chemistry preferred and some similar experience noted above OR PhD in Synthetic Organic Chemistry or related field preferred and some related postdoctoral experience required; 2+ years postdoctoral experience preferred

• Experience with cell culture and transient transfection in CHO and HEK293 cells

• Experience with antibody expression/production

• Knowledge of stable cell line development

• Knowledge of protein expression using a bioreactor

• Experience with AAV expression would be highly desirable

• Knowledge of standard molecular biology cloning techniques is a plus

• Able to execute experiments efficiently and suggest small process improvements

• Recognizes fundamental anomalies in data points and identifies issues in experiments / processes

• Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals

• Strong knowledge of scientific discipline

• Good knowledge of scientific principles, methods and techniques

• Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools

• Strong computer skills

• Good problem-solving, analytical thinking skills

• Detail oriented

• Ability to meet deadlines

• Excellent communication skills with the ability to collaborate with cross-functional scientists

• Ability to maintain accurate detailed documentation of experiments essential

• Willingness and ability to work both independently and as part of a team

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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

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